The present study examined the effects of Stress Lecture on stress related variables in college students. The students in 'Understanding and Management of Stress' class were assigned to experimental group (Stress Lecture Group) and the students in 'Psychology' class to control group (Psychology Lecture Group). Stress related variables were measured with stress vulerability test, stress reactions test, and positive reactions test. Stress vulnerability test consists of 7 subscales (Healthy Diet, Avoiding Alcohol and Cigarettes, Cigarettes, Emotional Well-Being, Relaxation and Enjoyment, Balance between Home Work, Self-Understanding and Acceptance), which measure the degree of health in everyday life style. Stress reactions test consists of 4 subcales (Emotional Reactions, Disruption of Though Processes, Physical Illness, Behavioral Signs), which measure various types of stress responses. Positive reactions test measures various responses which contrast with stress responses. The tests were given at the beginning and the end of the semester. The results were as follows. We could find that Stress Lecture Group showed more changes in more subscales of the tests than Phychology Lecture Group. Lastly we discuss these results and limitations of the present study.