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- Original Article 우울 및 스트레스 정도에 따른 혈중 호모시스테인 농도
- 임창욱1ㆍ문지현1ㆍ김현주1,2ㆍ공미희1,2
- Plasma Homocysteine Concentraton according to the Depression and Degree of Stress
- Chang-Wook Lim1, Ji Hyun Moon1, Hyeon Ju Kim1,2, Mihee Kong1,2
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STRESS 2015;23(4):179-185
DOI: https://doi.org/10.17547/kjsr.2015.23.4.179
Published online: December 31, 2015
1제주대학교병원 가정의학과, 2제주대학교 의학전문대학원 가정의학교실
1Department of Family Medicine, Jeju National University Hospital, 2Department of Family Medicine, School of Medicine, Jeju National University, Jeju, Korea
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Abstract
In this study, we investigated plasma homocysteine concentration according to the depression and degree of stress. The study subjects were 1,395 adults aged over 20 years who visited a health promotion center. Medical history was recorded through a self-reported questionnaire and physical examination was performed on all subjects. We measured plasma homocysteine by blood sampling after fasting over 8 hours. To determine depression, we used CES-D in the subjects below the age of 65 and GDS over the age of 65. The stress group is divided into three subgruoups by using BEPSI. We adjusted for all variables that affect the homocysteine. The homocysteine concentration was not associated with depression regardless age and sex. There was significant differentiation of plasma homocysteine concentration according the degree of stress in men, but no differentiation in Women. This study showed no relationship between depression and plasma homocysteine concentration. We found that men in high stress group had a tendency for higher plasma homocysteine concentration. (Korean J Str Res 2015;23:179∼185)
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