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Original Article 공황장애 환자의 정서증상 및 긍정 심리요인과 심박 변이도의 연관
Correlations of Psychiatric Symptoms and Positive Psychological Factors with Heart Rate Variability (HRV) in Patients of Panic Disorder
Dong-Hyun Nam, Jung-Ah Min, Jeong-Ho Chae
STRESS 2012;20(3):221-128
Published online: September 30, 2012
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가톨릭대학교 의과대학 정신건강의학교실

Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea

The heart rate variability (HRV) has been suggested as a possible biological marker for panic disorder. Given that clinical implications of positive psychological factors were reported in anxiety disorder, we investigated the correlations between HRV and psychiatric symptoms including depression or anxiety as well as positive psychological factors such as resilience, gratitude, hope in patients of panic disorder. A total of 36 patients who diagnosed as panic disorder according to DSM IV-TR were recruited. HRV data were collected using 5-minute electrocardiographic recording and time domain parameters were calculated. Self-report questionnaires including State-Trait Anxiety Inventory (STAI), Beck Depression Inventory (BDI), Connor-Davidson Resilience Scale (CD-RISC), The Gratitude Questionnaire-Six Item Form (GQ-6) and The State Hope Scale (SHS) were used to measure anxiety, depression, resilience, gratitude, and hope, respectively. To identify the relationship between HRV parameters and these psychological variables, correlation analysis was performed. The scores of State Anxiety Inventory (SAI) showed a significant negative correlation with SDNN (Standard deviation of the normal to normal interval) of HRV parameters. However, the scores of Trait Anxiety Inventory (TAI), depression (BDI), and positive psychological factors (resilience, gratitude, and hope) had no significant correlations with HRV parameters. The results of present study revealed that state anxiety was negatively correlated with the marker of heart rate variability in patients with panic disorder. These associations might suggest the relationship between anxiety and autonomic symptoms in panic disorder. (Korean J Str Res 2012;20:221∼228)

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