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Original Article Chronic Physical Stress가 방광의 안정성에 미치는 영향
전종현·정우식·윤하나
The Effect of Chronic Physical Stress on Bladder Stability
Jong Hyeon Jun, Woo Sik Chung and Hana Yoon
STRESS 2006;14(3):211-218
DOI: https://doi.org/
Published online: September 30, 2006

이화여자대학교 의과학연구소 비뇨기과학교실



Department of Urology, Medical Research Center, Ewha Womans University College of Medicine

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This study was designed to examine the effect of stress on the pathophysiology of bladder stability via Rho-kinase that are required for muscle contraction and relaxation within the bladder. In addition, through animal model using metabolic cage, it was proven that a stressful environment can induce urinary incontinence. The results also showed that levels of ROKՁ all significantly increased with continued application of stress. In this study the control group placed under normal conditions and the test group under stressful conditions were monitored in Metabolic cages for 27 days. The frequency of urination increased significantly in the stress group and the amount of urine that decreased on the contrary showed symptoms of overactive bladder. This study, therefore, provides evidence which support the hypothesis that stress plays an important patho-physiological role in bladder overactivity. (Korean J Str Res 2006;14:211∼218)

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