*한국과학기술원(KAIST) 생명과학과, †한국과학기술연구원(KIST) 신경과학연구센터
*Department of Biological Sciences, Korea Advanced Institute of Science and Technology, †Center for Neural Science and Korea Institute of Science and Technology (KIST)
Conventional animal models of stress including immobility or electrical foot shocks are far from real life. As psychosocial diseases are increasing in human, animal models for reflecting phycosocial stress have been focus and developed. Establishement of phsychosocial stress models using mouse, where transgenic technologies and inbred strains are available, allows us to study moelcular mechanisms underlying the pathogenesis of stress. This paper is a review of the phychosocial stress models including social isoaltion, social defeat, and innate fear model in mice. (Korean J Str Res 2006;14:49∼51)