The relationship of stress to illness has been the subject of research that examines broadly different conceptualizations of stress across a wide variety of psychosomatic disorder. Theories of stress can be labeled as stimulus oriented, response oriented, or interactional. The stimulus oriented construct views stress as a property of the environment that is imposed on the individual in a demanding. The response orientation to stress postulates that it is not the mere presence of an extermal stressor, but rather the response of the individual to his environment that defines stress. The interactional orientation emphasizes individual characteristics as the major mediators between environmental stimulus and the response evoked. This paper was discussed different constructs of stress theories, assessment method and limitation of self-reported measurements.