The aim of this study is to verify the effects of EDT on stress, fatigue, sleep and HRV in nurses. The study was a quasi-experiment using nonequivalent control group pretest-posttest design.

Experimental treatment was to contact EDT 3 points on the body surface. EDT touch used the first fingerprint of the thumb for 3 minutes on the frontal branch of superficial temporal area, 3 minutes on the facial area, and 4 minutes on the axillary area. EDT was applied 10 minutes, twice a week for 5 weeks.

Data were analyzed with SPSS 23.0 program. As a result, stress, fatigue, sleep, and HRV were statistically significant difference in both groups.

EDT can be used not only for nurses’ health maintenance and promotion but also for independent nursing intervention at clinical practice.