- Association between Suicidal Ideation and Blood Cadmium Levels Based on the 3rd to 7th Korea National Health and Nutrition Examination Surveys
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Sunmi Kim
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STRESS. 2024;32(1):46-52. Published online March 28, 2024
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DOI: https://doi.org/10.17547/kjsr.2024.32.1.46
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Abstract
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- Background
This study aimed to determine the association between blood cadmium levels and suicidal ideation.
Methods Using data from the 3rd to 7th Korea National Health and Nutrition Examination Surveys, the geometric mean of blood cadmium levels according to suicidal ideation was compared using multiple linear regression analyses in male and female adults. The frequency of suicidal ideation according to the blood cadmium levels was also compared using multiple logistic regression models.
Results In total, 6,877 men and 6,698 women were included in the study. When adjusting for all potential confounding factors, the geometric mean of blood cadmium levels was significantly higher in participants with suicidal ideation than in those without suicidal ideation in both men (0.92 ng/ml [95% confidence interval 0.87∼0.97 ng/ml] vs. 0.86 ng/ml [0.84∼0.88 ng/ml]; p=.026) and women (1.05 ng/ml [95% confidence interval 1.01∼1.10 ng/ml] vs. 0.99 ng/ml [0.98∼1.02 ng/ml]; p=.006). After adjusting for potential confounders, the frequency of suicidal ideation significantly increased as blood cadmium levels increased in men (p for trend=.014) and women (p for trend=.034).
Conclusions Results revealed an association between blood cadmium levels and suicidal ideation in Korean adults.
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